Replies to post #27768 on Marker Therapeutics Inc (MRKR)

[poods]

Just my opinion but i think Multi-TAA would be a lock for accelerated approval if we see another CR. I think the correlation with antigen/epitope spreading makes the case even much stronger.
https://undark.org/article/fda-drugs-accelerated-approval/

[poods]

By the way, some of the questions asked yesterday were a bit redundant. They didn't accept questions from individual investors. I submitted a simple question. How much epitope/antigen spreading are they seeing in non responders? That was not shown in the data, only a statement that there was a correlation and it was clear that all the responders had impressive antigen spreading. If this phenomenon is indeed restricted to responders primarily, it strengthens the cause/effect relationship. That would be a stronger selling point to the FDA that the treatment works as advertised.