Replies to post #201609 on Amarin Corp Plc (AMRN)

[roadkilll]

What Are the Real Differences Between EPA and DHA?

First, EPA is an inhibitor of the enzyme delta-5-desaturase (D5D) that produces AA (1). The more EPA you have in the diet, the less AA you produce. This essentially chokes off the supply of AA necessary for the production of pro-inflammatory eicosanoids (prostaglandins, thromboxanes, leukotrienes, etc.). DHA is not an inhibitor of this enzyme because it can’t fit into the active catalytic site of the enzyme due to its larger spatial size...This is why measuring the AA/EPA ratio is such a powerful predictor of the state of cellular inflammation in your body.

Psychology Today
2012
Barry Sears Ph.D

[1bill]

concerning my amrn corp. wtf , I was under the belief this was disseminated during the nme nce debacle [fda changed the wording] if I remember, was resolved. though appreciate it all j, and only hope most would graduate from cluelessness, thanks again for your efforts, someone has to be coherent, with respect to our fda , know this