Flip I know you are not a fan of Avastin but consider this statement
"Therefore, we hypothesized that antiangiogenic therapy may be inducing a highly inflammatory environment and creating resistance by promoting a proneural to mesenchymal phenotypic shift."
If Mesenchymal = The best genetic profile and they actually have a way to make more patients Mesenchymal this would increase the overall percentage of longterm Surviors.