Replies to post #231058 on NorthWest Biotherapeutics Inc (NWBO)

[iwasadiver]

The UCLA based CI combo trial (with -L) is fairly clearly nixed as they paid Cognate to restart Direct but not -L.

Great deductive reasoning. How much do you want to bet you’re wrong? Same on Germany. Fairly clearly? Haha

[Evaluate]

you wrote:

The only upcoming trial we are looking at in the next 6 months is a 10 patient P1 (expandable to 24) trial of Direct in brain mets.

ASCO presentation included:
22’37: Speaking in regards to DCVax-Direct trials, Dr B mentioned we are just going to “lift the tip of the veil of some of the things we are working on”
23’05: I will talk about 2 trials, but it is only a sample of the other things we are working on. I think you can derive some of the flavor of the other things we are working on from the things I showed you on the previous slide = slide 15 (which included: “DCVax-Direct shows the potential for combination therapy with immune checkpoint inhibitors”)

So: I get the impression from Dr B that there could be a lot of additional planning going on beyond the 2 trials that he highlighted.
And ... I get the impression that he was hinting that some combination trials with Checkpoint inhibitors could still be in the works.