Replies to post #229269 on NorthWest Biotherapeutics Inc (NWBO)

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https://www.sciencedirect.com/science/article/pii/S0092867413012087
Cell, The Somatic Genomic Landscape of Glioblastoma, Volume 155, Issue 2, 10 October 2013, Pages 462-477

For SOC treatment with TMZ, Correlative analyses confirm that the survival advantage of the proneural subtype is conferred by the G-CIMP phenotype, and MGMT DNA methylation may be a predictive biomarker for treatment response only in classical subtype GBM.

Whereas, it appears, but we need to see results, that DCVax-L gets responses in methylated MGMT in mesenchymal as well as classical.