Replies to post #193494 on Amarin Corp Plc (AMRN)

[Planetrader]

Here is the Twitter feed.

"Eicosapentaenoic acid in combination w/ EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux"

"...we sought to investigate the anti-tumor effect of..Vascepa.." $AMRN

https://t.co/Md1NXgrE7p pic.twitter.com/KXv58sIavJ

— TerraPharma (@TerraPharma1) May 23, 2019

[jessellivermore]

Planetrader...and raf

No..This is the article raf referenced a few days ago...This is what I have been posting about...

One thing I did not include is the fact that cholesterol levels in the plasma membranes are important determiners of cellular apoptosis..Increased cholesterol on the plasma membranes increases membrane stiffness which increases apoptosis..So suppression of an important cholesterol transporter drug enhances the effect of ERPHA2 suppression and EPA..Statins might even promote tumor survival by lowering membrane levels..

In this paper there was no mention of serious side effects of the drugs used to suppress EPHA2 receptors...Dasatinib was the drug they settled on

":>) JL