However nidan was referencing current and future trials talking about leading the way. My reference to “the new trials” was speaking more to that as nidan’s contention is that Anavex is bringing more to the table than getting an approval. He is saying Anavex trials are the prototype for the redesign of how things will be done. And he is also saying, if I hear him right that, there can be no going back. Which implies this is happening.