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nidan7500

04/21/19 4:10 PM

#190112 RE: ElsaSara #190111

ElsaSara, this information is helpful, thank you.

- Only Pdd trial In Europe.
- No improvements in last 15 years.
- He explained the trial..trial with placebo.., first step 2 weeks of screening ,14 weeks taking the drug/placebo, nobody knows what the patient is taking..
-He explained Pd/ pdd , ..main problem quality of life.., he mentioned that one of the symptoms associated to Pd is that it affects to sleep.
- Only in Spain about 300 k patients with Pd. He also said that Anavex chose Spain but he didn´t say the reason, but he said that Spain is a top country in the world in investigation.
-Full enrollment for screening he estimated probably by May, first step two weeks of screening, 150 patients for screening. They use test moca( between 13- 23 points) . Main problem for patients that are finally not include is lack of vitamine b12.
- If they get + results, next step a phase 3 with more patients.



Expecting as Precision Medicine trail protocols become a focus that risk of trial misses will decrease significantly. Biotech investment models should shift to the left.