Replies to post #189948 on Anavex Life Sciences Corp (AVXL)

[HMB2010]

Thank you. Great read.

[nidan7500]

A step in the right direction is represented by the recent formulation of unbiased agnostic biomarker classification systems for AD and neurodegenerative diseases to identify and grade risk in normal elderly people. The goal is to identify the full spectrum of the specific biological alterations in elderly individuals at risk long before the appearance of first clinical symptoms.

A recurring theme w/HH. Blocking and tackling basics.

[Penny Double]

Why use a shotgun when you have a rifle?

Sniper (precision) X ( biomarkers)Mark's the spot!

[roygbiv]

S.Kettering PM gene databse for cancer only considers a small segment of gene mutations(468), via MSK-IMPACT. (not PM, imo)

https://www.mskcc.org/msk-impact


It seems the approach/method below fits the PM bill and would work for many diseases, including CNS.

*Includes whole genome/exome sequencing of 20,000 genes and 3 billion base pairs

*Incorporates whole transcriptome sequencing of over 200,000 RNA transcripts

*Compares a patient’s tumor genome to their normal genome and provides pharmacogenomic analysis for potential drug toxicity and/or interactions

https://nanthealth.com/gps-cancer/


https://clinicaltrials.gov/ct2/show/NCT03073473


Thanks!