I understand your position regarding the possible consequence of not hitting the PFS endpoint while meeting the OS endpoint. However, I could see it not being a problem if on the day they issued the topline PR they also scheduled a CC for analysts (and us). Undoubtedly, the analysts would ask what is the impact of PFS failing. If they can satisfactorily explain why it's all about OS, tout the OS numbers, and say, upon our discussions w the Agency(s), they are in agreement that it will be evaluated based on OS then I can see that PFS could be neutralized and won't have much impact on the share price but they'll have to be on their game for sure.