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03/19/19 10:53 AM

#181824 RE: rfj1862 #181821

RFJ - I think the importance of the AA/EPA ratio is not so much that it's a surrogate marker but the possibility that it could be THE marker that triages patients to a risk category that determines treatment.

For example, a patient may have CVD on a statin but has a great ratio - it may be that they do not benefit from Vascepa. Or vice versa they are lower risk primary prevention with a terrible ratio and they have a great RRR with V use.