DM, This is my first big Bio/Pharm individual stock investment for me since Perigrine Pharm in the 90's IIRC. Welcome to startup BIO/Pharm investing. It's not for the faint of heart or for 'all in investing' but aside from the BS manipulations and anxiety associated with it, It can pay big. I find it to be more like gambling than investing where, statistically, the house has the advantage. Hopefully and likely, just another bump in the road to riches. JMO and GL.