Thx georgejji: Could it be that the knowledge base on AVXL SAB have encouraged/guided Dr.M. to avoid US trials until FDA gets cleaned up? Curious that progress in other countries has not translated to USA. AVXL SAB are all well informed, senior people who understand how the blocks go together. IMO, there is more to this than meets the eye. Was Dr.G. just walking away was an indicator of how broken the place really is. Stuff happens.