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iclight

01/31/19 10:50 AM

#211264 RE: Andy2018 #211249

I couldn't care less about AVEO. Goes to show that the DCVax trial is doomed.

BioInfo

01/31/19 1:59 PM

#211345 RE: Andy2018 #211249

FDA and folks failed to understand immunotherapy and that's why they established PFS as primary. Immune system takes time to work, you may progress initially but eventually tumor may start to shrink over time. How hard is it to understand we have OS like no other.
Safety profile - check
OS - check
PFS - call it check as it must have been at par if not better than SOC.

If vaccine was not working, everyone would not be living longer as everyone witched to treatment arm.