Replies to post #209296 on NorthWest Biotherapeutics Inc (NWBO)

[CogDiss 1188X]

Thanks Gus! Good stuff in itself and also triggered reflections on ways to effectively present complex info.

[sentiment_stocks]

Thanks for posting that video Gus. I hadn't seen it before and thought it was very interesting.

Around minute 4, the video addresses B cells. And every time I think of B cells, I think about how the CAR-T therapy targets the CD19 they carry, and when it target that to get rid of the malignant B cells, it also targets the healthy B cells, depleting the body of all of them. If another infection or tumor hits the same person, are they limited by the lack of B cells in the body? They can counteract this by injecting Immunoglobulin regularly into that person, but does it work as well?

And what happens to the memory B cells, a sub-type of the B cells? These are the cells that stick around in the body to help make you more immune to a disease or infection should it try to return. How do they retain B cell immunity if they are all gone?