Replies to post #208668 on NorthWest Biotherapeutics Inc (NWBO)

[exwannabe]

Is this the “unblinding” of the blinded trial that many seem to believe happened? If so, what evidence is there that the trial has in fact been unblinded in this way?

As Flipper could school you on, "unblinded" has various flavours.

What we know for a fact is that for 2 years they have been presenting data that could not be known w/o access to information on patients being on treatment or control.

In the JTM paper, they attributed this knowledge to looking into shipping records.

Call it what you wish, but the trial is leaking unblended data via the shipping records.

[Doc logic]

CogDiss1188X,

The question is whether or not this is considered a true unblinding with alpha spend being utilized or not. Knowing Linda, she would vociferously argue against this being a true unblinding so as to protect that alpha spend. I don't think the bears like the idea that this might have been what happened and that Linda had a plan to defend NWBO if this ever became a question. Sneaky lawyers lol. Best wishes.