DES is big money and a reoccurring revenue stream. Unlike Reduce-it this would be a very easy/quick study for Amarin to do. This is Zip's expertise, but the results of tear film production and composition are quantifiable. I would think all you would need is 6 months at most on Vascepa to see changes.
A lifetime ago in board terms, I linked to a book titled IIRC, something like "Diseases of the Surface of the Eye" published around 2010. There were numerous citations of Omega 3's and eye diseases. Again, IIRC, someone even had a go at an O3 drug. There are possibilities and they have long been suspected/recognized.