LOL, THE "TRIAL FAILED". The trial failed what exactly. If you mean that the vaccine caused TILs to to attack the tumor location - also known as swelling and to the naked eye using the wrong measuring stick this could appear to be progression. Then maybe using the wrong measuring tools the trial failed. But we are way past PFS, we will have enough data to show long term outcomes and you can not tell me at this time that the 3 and 4 years survival numbers will not be good. I can't tell you definitively that they will be good, but it sure looks that way.
You see the propeller heads will call it progression when it is in fact aggression.
Just like the hack jobs that said mineral oil caused a minor increase in LDL in AMRN's reduce it trial, too bad that trial was measuring outcomes. Just like here if we see a little more progression(quote un quote) in the treatment arm but these same patients are living much longer, how can it be , or if it is does it matter. If you have asymptomatic "progression" and go on to live 2 years longer or more than you should, that is actually a good thing.
We're holding the ace-king of spades in the pocket with two spades on the board, if the un-blinding reveals another spade, we will have the nut flush. We know as a whole they are living longer, we need to see the un-blinded data. If the un blinding goes the way we think it will not only will it show the treatment arm is living longer, but survival numbers will improve because we are being weighed down by the placebo arm in the blended numbers.
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