After the CTAD presentation I predict huge optimism coupled with dismay as to how the cabal has manipulated the price down so they can get the cheapies.
We need to see news on the super responders. Yes, we know there are not many of them but if they have continued on their exceptional paths then BINGO. They are evidence of a binary event. Now, doing more work to understand how their CNS is wired or different from others is an important step.
As Biostockclub has suggested, at some point the Precision Medicine process of discovery has to take the point. Put the shotguns away boys and start digging. IMO, this is it, the CTAD conference has AVXL set up to score bigly, really YYUUUUUGE. I also expect we will get some clues before the event. On the other hand, if BIIB keeps up with their standard practice of massive PR's around conference time then the smoke will get in the way. So, if no massive smoke then look for good things.