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10/09/18 10:39 AM

#148572 RE: VuBru #148562

VuBru, thanks for your helpful comments . I believe it was TTE who had done some detailed calculations on the actual p value of Reduce-It in the order of 0.00000001. Should not this magnitude of p value and the 25% RRR of the PE in Reduce-It give more wiggle room for significance in SE if one looks at the more modest PCSK9 trial data as a comparison. I do not do Statistics for my day job nor even as a hobby, but I believe you, AVII, TTE and others on this board are able to tease such figures and predictions in Hierarchy of SE quite effortlessly with a more in depth background in Statistics.