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jimmy_mcyoloswag

09/30/18 7:41 AM

#167225 RE: Investor2014 #167223

It seems that activation of the S1R or MR by 2-73 is the missing link, allowing buffering of pathological calcium signalling to less cytotoxic levels (the fire truck analogy). But apparently only if there is too much. A low pass filter for calcium load on cells if you will.

If precarious calcium concentrations are reached calcium is buffered, if not, no biggie..