Nidan, Good perspectives. The fact that most CNS diseases are a process of slow neuro-degeneration, which takes years/decades to progress to a debilitating state, should give us a clue that regeneration may take equally as long. In that context 2-73 initial results appear to be amazing. However, its true curative effects may take many years in ongoing P4's to validate. The efficacy in pri and mild Alzheimer's may be more rapid but, harder to discern. On the flip side, clearing the brain of amyloid plaque and tau may be easier to demonstrate, like sweeping up a workshop of sawdust. But, the sweepers have yet to demonstrate that the workshop works any better.
The medical community and the public have become use to the failures, so we can expect skepticism and slow reaction to 2-73's positive data. That's why conducting our P2b/3 in Australia is brilliant as their "Getter done " attitude will measurably accelerate 2-73's approval and use.
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