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survivor1x

09/17/18 3:03 PM

#190002 RE: JRIII #190001

They "remain blinded" how do you know they have failed PFS or OS? Do you have the unblind data that company doesn't have? Switching gears to capture a long tail doesn't mean they will not also hit PFS or OS targets, it just means they didn't look as early as they would in a chemo trial that usually have no tail.

CherryTree1

09/17/18 3:43 PM

#190007 RE: JRIII #190001

This is a nonsensical allegation JR:

It should be obvious to everyone that the trial did not meet its targets because if it had met its targets, I think everyone here would agree (unless they are disingenuous) that the company would have blasted that news across every PR news wire in the world.


The trial is blinded. It would be impossible for them to know if they did or did not meet targets. The only thing they can measure to determine when to end of the trial is the number of events.
They made this announcement in early 2017:
https://www.nwbio.com/nw-bio-announces-lifting-clinical-hold-dcvax-l-phase-iii-trial-fda-progression-free-survival-events-reached-overall-survival-events-not-yet-reached/

NW Bio Announces Lifting of Clinical Hold on DCVax®-L Phase III Trial By FDA; Progression-Free Survival Events Reached; Overall Survival Events Not Yet Reached