Replies to post #185583 on NorthWest Biotherapeutics Inc (NWBO)

[flipper44]

"If there indeed 74 patients not on the chart, then we can make some assumptions, like that there were 74 patients that lived past 36 months." -- Senti

It looks like the study contests your counting.

182 patients are ≥36 months past surgery; 44 of these (24.2%) have lived ≥36 months and have a KM-derived mOS of 88.2 months. -- DCVAX-L blinded results drawn from March 2017 data cutoff.

[biotrade49]

When the paper first came out, I did a careful count of the deaths and censored events and came to the same conclusion as you did. There were well over 44 patients that were not on the published curve. I could not reconcile this contradiction so I just set the numbers aside. My counting did not break it down into time increments as you did, so to compare with your numbers I went back and recounted. My numbers (see below) are very close to your counts.

First 12 mo (7,34) (censored, deaths)
12 to 18 mo (4,62)
18 to 24 mo (37,47)
24 to 30 mo (21,23)
30 to 36 mo (7,16)

11 LTFU
182 died
65 censored

to equal 258 patients

331 - 258 = 73 patients not on the chart