Replies to post #184834 on NorthWest Biotherapeutics Inc (NWBO)

[flipper44]

I have not asked for unblinding right now. Instead, I have asked for what event rate it is they are looking for. Right now, there is no objective endpoint given. None. Zero. Nada. Quit falling for their “need” for secrecy. Giving an objective endpoint standard they are looking for is not the same as telling us what day they will stop. This is a public company for God’s sake and they have shirked any responsibility for providing any reasonable standard to end. Have a good summer. Personally, I hypothesize the treatment km survival is not going to change dramatically after they have incorporated this refresh. It could start to decline in potential future refreshes however due to the inclusion of sicker patients in the second half of the trial.

[doingmybest]

Umibe5690, I also defer to NWBO mgmt. for the unblinding decision based on the SAB's opinion. The company depends upon this decision. Though I am hopeful for 2018 unblinding and believe it will occur, I defer to mgmt. since they see much more than I do about this trial, including the very important SAB opinion.

[biosectinvestor]

i can't argue with your reasoning on the MB amateur "experts" who are not in a position to know enough to opine as confidently, as the company on all points. Nor is it always possible to tell everyone everything. Unfortunate. But true.