Replies to post #296100 on Elite Pharmaceuticals Inc (ELTP)

[Don'tDrinkTheKoolAid]

This could be the MIRACLE I was talking about that saves Elite.

[Gman24]

Appreciate you expertise as always. Your professional knowledge is priceless to this board.

[dr_lowenstein]

HOWEVER:::::::

We report no evidence for neuroprotection by in vivo pretreatment with therapeutically relevant isradipine plasma levels, or Cav1.3 LTCC deficiency in 6-OHDA-treated male mice.


Send to
J Neurosci. 2017 Jul 12;37(28):6761-6777. doi: 10.1523/JNEUROSCI.2946-16.2017. Epub 2017 Jun 7.
Lower Affinity of Isradipine for L-Type Ca2+ Channels during Substantia Nigra Dopamine Neuron-Like Activity: Implications for Neuroprotection in Parkinson's Disease.

[dr_lowenstein]

HOWEVER:


Brain Res. 2014 Sep 18;1581:1-11. doi: 10.1016/j.brainres.2014.07.014. Epub 2014 Jul 16.
Nifedipine and nimodipine protect dopaminergic substantia nigra neurons against axotomy-induced cell death in rat vibrosections via modulating inflammatory responses.
Daschil N1, Humpel C2.