Elite Pharmaceuticals Inc (ELTP): HOWEVER::::::: We report no evidence...

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Re: WeeZuhl post# 296100

Sunday, 07/29/2018 3:37:19 PM

Sunday, July 29, 2018 3:37:19 PM

HOWEVER:::::::

We report no evidence for neuroprotection by in vivo pretreatment with therapeutically relevant isradipine plasma levels, or Cav1.3 LTCC deficiency in 6-OHDA-treated male mice.

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J Neurosci. 2017 Jul 12;37(28):6761-6777. doi: 10.1523/JNEUROSCI.2946-16.2017. Epub 2017 Jun 7.
Lower Affinity of Isradipine for L-Type Ca2+ Channels during Substantia Nigra Dopamine Neuron-Like Activity: Implications for Neuroprotection in Parkinson's Disease.

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