Replies to post #160018 on Anavex Life Sciences Corp (AVXL)

[Talon38]

Sage, The big press release from the AAIC to national TV (CBS last night) was the results of the study of lowering blood pressure and apparent reduction in MCI. No mention of Biogen or Anavex. They took the safe middle course. It is fashionable these days to find disease cures in life style adjustments. Not knocking taking better care of one's body however, once a person is suffering from a full blown disease, lifestyle changes are an adjunct treatment in most cases.

[whippinsaw]

Biogen gets headlines on AAIC website and competition gets buried because biogen is a Platinum / gold star sponsor of AAIC.

2018 AAIC Sponsors

[nidan7500]

“This study represents an exciting step forward, away from the ‘magic bullet, one-size-fits-all’ drug development in Alzheimer’s, following the targeted therapy successes in the field of oncology,” Hampel said. “Our vision is that a precision medicine approach will allow us to more precisely treat and prevent key features of the cause and progression of Alzheimer’s. We are intrigued that several studies with this novel approach are now planned or underway.”

Sage4,mykroft,biostocker, others ...cannot thank you guys enough for carrying on the fight here. I have said before, "BIIB is a lot of things , but stupid ain't one of them." I guess that's a sentence.

Well, here we are a couple of days after the battle dust is clearing, counting the bodies, rethinking what's next. My assessment is that BIIB did have a plan and they executed it. I'll admit I thought they WAY overdid the upfront hype, media blitz and generally multi0media- article noise trying to convince the world the Amyloid Thesis was alive and well. Well, no one really bought it except the old schoolers like NBC/FOX and a few who actually carried excerpts. Unbelievable, they did it. Of course the whole thing was a complete farce but...SO WHAT. REALLY...days later who will remember how over the top they were...the distraction worked. NOW WHAT?
No one will believe a word these guys say for a long time, but they have been there before. We all know in this culture that when you have more money than the church you can get away with just about anything.
How long will it take until the BAN thing dies out (maybe it already has). I think we can say we finally understand why the BP establishment has not produced much of REAL medical value in decades. Hype does not cure medical illness and it never will but we keep thinking it will. HUH? BIIB sure got attention, yes it was a farce but, they did not get much of it on them...they came away clean, the BAN crew and their Japanese company is another story though. I saw the CEO on CNBC trying to answer a question on did BAN work...he squirmed and said .."we are working very hard on it", never answered the question. It was awful.

IMO, BIIB will be after AVXL with a passion. Partner, buy out, friendly or not they really have no choice. As someone already mentioned this whole smoke and mirrors thing has resulted in AVXL being a lot more powerful and visible. The sooner the better. Time for some real science around here.

[Talon38]

Sage, thanks, I forgot you posted that. I guess with our information buried only the LA Times picked up our story (the author is a seasoned reporter and must have been in attendance at Dr Hampel's presentation).

On another matter. While researching the issue of the NIH/NIA support of Alzheimer's research, I came across the NIH/NIA 2018 Alzheimer Summit in May. Going through the Agenda and list of participants, I was struck by how top-heavy in was in Academic researchers and how few Bio/Pharma's were involved. My conclusion was that if these were the "Movers and Shakers" in Alzheimer's drug and treatment development, then Universiies and Academic Research Institutions are getting the bulk of the support and research grants. Two different motivations, one wanting the research to go on and on and the other wanting to get the drugs to market. This is probably one of the FDA/NIH/NIA institutional hurdles that Scott and Janet are fighting to get over. To the point, the reason that the AAIC gave precedence to the Hypertension Study over a very promising drug(2-73) in their release of conference information.

What do you think?

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https://www.nia.nih.gov/research/nih-ad-summit-2018-program-agenda