I don't agree that the trading action (volume) today is related to upcoming announcemt. Today's is the last day of the Russell rebalancing and it looks like AVXL has been deleted from the Index. I hope this is the case and with this event behind us we should be in a position to resume the upward trend in expectation of news prior to or at the upcoming AAIC.
Just an opinion and not intended to be taken as fact.