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BioInfo

05/29/18 12:38 PM

#174348 RE: kabunushi #174342

Also add the fact that its blended mOS and pFS, actual will be separated in 3 groups.

1. SOC
2. DCVax Trial
3. Crossover.

obviously all these will have their own data and that needs to be separated to see real impact of DCVax. those who dont agree are in denial. Publication clearly says it hard to disect data and that will need to be done.
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AVII77

05/29/18 1:56 PM

#174401 RE: kabunushi #174342

As for "AVI77 who nailed it.", as I recall he said there's no way mOS is more than 20 months. That's a fairly big miss vs 23 months in my book - large enough to make the difference between likely approval vs likely non-approval.



perhaps you didn't read the paper.

The mOS of the overall ITT population (n?=?331) was 23.1 months from the time of surgery ........ The median time from surgery to randomization was 3.1 months.



So that's 20 months blended from Randomization.

And I didn't say "no more than 20 months", I said "20 months".

These blended results are unremarkable. Especially when we see 40% of the patients are MGMT+.