tred,
One of the the many insightful, well stated posts which I’ve read on the board. A shot in the arm - dosed with the potent drug: truth and with the added benefit of being reality. Thanks a million!
“and SMARTLY design new protocols to stop wasting time, money, and most importantly PEOPLES LIVES”
And:
“They are quietly assembling (with Fadirans help) a modern era of precision trials.”
And, if might add two more cents to everything you opined which I agree with in total: please consider the superior yet subtle concept of including Real World Experience or Evidence to what we already have.
In my mind, this is where our drug compound becomes a thing of beauty. With precision medicine, the targeted genetic biomarkers, will enrich population enrollment of the trials to their MTR - maximum tolerated Robustness. This should and will be enough (along with our safety profile) to solidify our trial results as the Undisputed Champion of the Standard of Care for AD, PD, Rett Syn, and other CNS diseases which derive from mitochondrial dysfunction.
And when the patients, caregivers, and doctors start talking in the RWE interviews portion of the trial, in accordance with new Sensible guidances, it will be the tiny number in the upper right hand corner which makes things exponential. 2 will be 4, pancakes will come with free bacon, good times will all be on a rollover minutes plan, it will sound as if all of the greats: Beethoven, Brahms, Mozart, Bach...and so on, and on, were all playing simultaneously. Music unearthly, and that it will be, because no one has ever heard anyone with Alzheimer’s talk about that particular state of mental darkness clearing away and the sun shining again where once there were only gathering storm clouds of the acutest kind - capable of grounding all incoming and outgoing aircraft of thought in the patient’s mind.
When the tower gives the “all clear” for thoughts to fly freely again on interrupted flight patterns through the brain cells, and even previous turbulence (insomnia, agitation, melancholy, confusion..,) is talked of as smooth flying again..., would simply love to be there. With each successful trial we exceed another level of Mach - at 767mph, Mach 1 we break the sound barrier, then M2, etc., on down the line..., all longs should swell knowing we co-piloted this baby, this new world of medicine, to safe landing. Our investments are our hands on the throttle.
Blue skies and friendly flying, And when we fly, we fly exponentially!
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