Replies to post #149708 on Anavex Life Sciences Corp (AVXL)

[Investor2014]

Why are we not all millionaires yet?

[nidan7500]

My Questions:

1. Compared to previous FDA guidance, describe in detail how the new FDA precision science process rules have impacted/influenced the A2-73 trials structure, metrics and planning process milestones for RS, AD, PD.? (eg. Timelines, metrics, including measurement devices/tools, RWE guidelines, pass/fail criteria).

2. How and How much will AI be used in planning, conducting and measuring trials results?

3. What specifically will you evaluate to validate that the claim of CNS Homeostasis restoration has been achieved with A2-73?

4. Do you have specific CNS cellular restoration or regeneration targets?

[powerwalker]

PA, my questions center on the Aussie trial:

1) Will an update on the Aussie trial be given soon ... a 130-week update, for instance?

2) Are those participants that have reached their third anniversary been allowed to continue taking 2-73? If so, does this mean, the number of participants is still 25?

3) Has any participant switched from a combo-therapy to a mono-therapy? If so, what has been the observations and results of such a move?

4) What is the condition of Ern, the pianist, the artist et al? Are there any more RWE and/or caretakers' comments?

5) Has Anavex applied to Australian Health Ministry for a BTD and/or AA (per American terms) of 2-73? If so, when is it likely to hear an answer?

6) Has Anavex intentionally put a "brick" on any follow-up news articles since the first ones came out?

Thanks for encouraging, PA. I sent this afternoon to IR.