CCXI 's Avaxopan is a potentially lucrative treatment for 3 rare kidney diseases.
All together, these rare conditions could reach a patient population of 40 - 100 K in either the U.S. or Europe.
In Europe, CCXI would only gain royalties from GNHAY (Vifor's)
In the U.S., CCXI would market the drug for itself.
CCXI has a cash runway until late 2019: but, there is a small possibilty that the company could become profitable w/o future dilution.
On the downside, there is a long way to fall if there are setbacks. As of 5/18 CCXI has MC = ~$500mn with ~$150mn in the bank