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Lykiri

04/08/18 6:24 AM

#166063 RE: Lykiri #165949

From Dr.Cobbs presentation (Individualized Treatments for Glioblastoma)
on March 14, 2018. (Cranial Conference)
https://www.facebook.com/SeattleScienceFoundation

Dr.Cobbs report on a patient (still alive after 15 years) with glioblastoma who developed an extremely robust human cytomegalovirus (HCMV)-specific CD8+ T-cell response to the pp65 CMV immunodominant epitope that began immediately after one injection of autologous tumor lysate-pulsed DC.(DCVAX-L min. 25)

I think he is talking about this case study:
“Induction of Cytomegalovirus-specific Anti-tumor Immunity after Autologous Tumor Lysate-pulsed Dendritic Cell Vaccination in a Patient with Glioblastoma”
Robert M. Prins, Ph.D., Timothy F. Cloughesy, M.D., and Linda M. Liau, M.D., Ph.D.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775501/

flipper44

04/08/18 8:12 AM

#166071 RE: Lykiri #165949

"Dr.Cobbs presentation (Individualized Treatments for Glioblastoma) was
on March 14, 2018. (Cranial Conference)
https://www.facebook.com/SeattleScienceFoundation

Video published on March 29." -- Dr. Cobbs



Thank you very much Lykiri. I think that is important, and possibly more relevant than one might otherwise think. I'm not saying he put March 2018 without the exact day on his slide to be clever, but from my perspective, it was clever. Look at what he is saying. Final analysis was still in process and not published yet.

Because the video was published on March 29, 2018, one might think there is a minimal chance something was turned into ASCO, because they were still analyzing. Of course most trials continue to be analyzed after topline results are arrived at, so it still left a chance. Still, March 29th was the last day one might be able to get a late breaking abstract in beyond the actual LBA deadline of March 15th -- if they received permission.

Because we learned Dr. Cobbs spoke on the 14th of March (Thanks to your due diligence), the pieces of the puzzle still might point toward analysis potentially being submitted by March 15th. Even if it was not, it still could have been submitted by March 29th, if permission was granted. In other words, they had more time if they needed it. (Assuming they may have been trying to submit anything)