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thewellnessway

03/13/18 10:51 AM

#59206 RE: gbrown6332 #59199

Also...

The events leave Advaxis facing the conundrum of why a patient who had previously tolerated both drugs died of respiratory failure. Prior studies suggest Imfinzi may be the culprit. One patient had died of respiratory failure in AstraZeneca’s phase 3 trial of Imfinzi in lung cancer at the time it reported data in September, and analysts at Jefferies uncovered other incidents linked to the drug and checkpoint inhibitors in general.

From: https://www.fiercebiotech.com/biotech/fda-hits-advaxis-clinical-hold-after-death-astrazeneca-combination-trial
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Traderbx

03/13/18 10:56 AM

#59209 RE: gbrown6332 #59199

Here is some more confirmation that Imfinzi could be the culprit:

"Medical problems began following the first dose of Imfinzi but were managed, Advaxis CSO Robert Petit said on a call with investors. "

Source:

https://www.fiercebiotech.com/biotech/fda-hits-advaxis-clinical-hold-after-death-astrazeneca-combination-trial