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Replies to post #137457 on Anavex Life Sciences Corp (AVXL)
Renovascular hypertension in a child with Rett's syndrome.
Uhari M, Rantala H.
Abstract
A girl with Rett's syndrome and renovascular hypertension because of a stenosis in the right renal artery is described. The girl was operated on twice because of the stenosis. Her blood pressure normalized after the second operation in which the artery was reconstructed. High blood pressure causes neurological symptoms which may be difficult to distinguish from the basic disease. The importance of the measurement of blood pressure in every child with neurological symptoms is emphasized. The possibility of an association between renovascular hypertension and Rett's syndrome should be studied in large series.
Blood pressure fluctuation and hypertension in patients with Parkinson's disease
Tetsuro Tsukamoto,1 Yoshimi Kitano,2 and Sadako Kuno3
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Abstract
Objectives
Blood pressure (BP) abnormalities have been known in Parkinson's disease (PD) patients. The present study aimed at determining how the BPs of PD patients fluctuate in a day.
Methods
A total of 37 PD patients and 44 OD (other disease) patients, all of who were inpatients, were monitored every 30 min by 24-h ambulatory blood pressure monitoring (ABPM).
Results
The average systolic BP and the number of patients who showed postprandial hypotension were not different between the two groups. However, occurrence of nocturnal hypertension, BP fluctuation of over 100 mmHg in a day and BP of over 200 mmHg were significantly more frequently observed in the PD patients than in the OD patients. In the PD patients, these parameters were not different between those who were suffering from the disease for less than 10 years and those with the disease for 10 years or longer, as well as between those who had a Hoehn–Yahr staging scale of 2–3 and those with a scale of 4–5.
