Replies to post #118851 on Amarin Corp Plc (AMRN)

[jessellivermore]

hayshaw...

This market release is full of BS like most things "Krill"...Krill might technically not be "fish", but the the EPA and the DHA in their oil is in essence the same as is in fish oil..They get theirs from micro algae like every one else in the ocean...This means the pathophysiological effects are largely the same....

Krillistas claim their oil is superior to the esterfied n-3s seen in Lovaza and Amarin...Krill oil is in the free fatty acid (triglyceride) configuration and therefore more of the n-3s are absorbed from the gut...iimplying you get higher levels in the bloodstream...This maybe true in certain situations, but the FDA does not agree that krill oil produces higher blood levels....

There are lots of other problems...China and krill oil go together like oil and water...The krill are small animals that live in the southern hemisphere oceans surrounding Antarctica...This is also incidentally the nesting places for any number of whales that feed on the krill...That not only makes the harvesting of krill a dicey endeavor...but it draws the attention of several international agencies that monitor and limit the amount of krill that can be taken before the harvesters are eating the whales' lunch...And believe me that comes way before you got enough to satisfy China...

Krill oil is also very unstable and the harvested krill need to be frozen immediately after they come out of the water otherwise they turn into a rancid mess..

So tell me no tales about how krill oil which can not be fractionated into high concentrated EPA without esterifying it can not even meet the CVD (not the hypertrigyceride Pancreatitis) of New Jersey...Much less the USA and China...

I have noted that krill oil draws in the same wannabes that drive Range Rovers, and use to drive Volvos.

":>) JL

[sts66]

Why is Acasti and their China partner wasting money creating a slightly modified version of Lozaza? Insurers will never cover it in the US, they'll force patients to use GL instead, unless CaPre lowers TGs by a large % better than L/GL, and even if it does I can still see insurers saying "step therapy, must fail on GL first", especially since GL is very cheap now. Also, CaPre is 4 g in a single capsule?!? How on earth are you supposed to swallow a horse pill like that?!? AMRN came out with the 500 mg version of V because some people have trouble swallowing the 1 g capsule - and I can verify it's the largest pill/capsule amongst all the DS and Rx drugs I take, but it's shape and gel coating make it relatively easy to swallow for me, but I cannot imagine being able to take a capsule 4x the size w/o gagging or choking. Obviously the patients in their small P2 trial managed to do it somehow, but I seriously wonder how many people are going to be able to do it, especially if they have a strong gag reflex like me.