Replies to post #3070 on Insmed Inc (INSM)

[io_io]

<<<"Conclusions: Seven days treatment with IGF-I/IGFBP-3 complex enhanced overnight insulin sensitivity and reduced GH levels, but there was no effect on glomerular hyperfiltration or albumin excretion rates.">>>


Diabetes - can someone tell me is this good or bad ?

- because I know nothing about Diabetes -

TiA !

[elmono]

I don't think this is such good news', since the objective wasn't met:


Objective of the study:

Young adults with type 1 diabetes mellitus (T1DM) have increased glomerular filtration rate (GFR), which may mediate progressive renal disease and microalbuminuria. This may be secondary to low concentrations of insulin-like growth factor (IGF)-I and GH hypersecretion. We tested the hypothesis that restoration of circulating IGF-I concentrations in young adults with T1DM might suppress GH secretion, GFR and urinary albumin excretion.


Conclusion:

.....but there was no effect on glomerular hyperfiltration or albumin excretion rates......