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Re: Christiaan F post# 3070

Friday, 09/29/2006 5:41:22 PM

Friday, September 29, 2006 5:41:22 PM

Post# of 6489
I don't think this is such good news', since the objective wasn't met:


Objective of the study:

Young adults with type 1 diabetes mellitus (T1DM) have increased glomerular filtration rate (GFR), which may mediate progressive renal disease and microalbuminuria. This may be secondary to low concentrations of insulin-like growth factor (IGF)-I and GH hypersecretion. We tested the hypothesis that restoration of circulating IGF-I concentrations in young adults with T1DM might suppress GH secretion, GFR and urinary albumin excretion.


Conclusion:

.....but there was no effect on glomerular hyperfiltration or albumin excretion rates......

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