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falconer66a

11/13/17 1:27 PM

#130293 RE: F1ash #130291

I Was Wrong, Anavex in the Table

I was in error. I didn't see Anavex listed in any of the paper's text; but it's in a table. Nothing new on it, just what we know. Page 370

But nice to be listed. The rest of the Alzheimer's research and treatment community need to learn of the Anavex details. Has more promise than anything referenced in the paper.

https://www.researchgate.net/publication/320161874_The_present_and_future_of_pharmacotherapy_of_Alzheimer%27s_disease_A_comprehensive_review


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Investor2014

11/13/17 1:49 PM

#130298 RE: F1ash #130291

Have you found any recent references to MK-7622 in P3?

I can only find these references e.g.:

Phase 1
https://clinicaltrials.gov/ct2/show/NCT01852110

Phase 2
https://www.nia.nih.gov/alzheimers/clinical-trials/mk-7622-people-alzheimers-disease-taking-donepezil

This trial is listed as Terminated. Not sure why.

According to: http://adisinsight.springer.com/drugs/800038117 MK-7622 is a "Muscarinic M1 receptor modulators", not M4.