Replies to post #116844 on Amarin Corp Plc (AMRN)

[HDGabor]

K-

Yes, it is not easy to find a relevant data / research :-) ... BUT:

Influenza Vaccination of Persons with Cardiovascular Disease in the United States

Estimated influenza vaccination coverage in age-specific subgroups of persons with heart disease or with no reported high-risk condition varied by less than 11% from the 1996–97 through 2000–2001 influenza seasons, with a steady increase observed from 1996–97 through 1999–2000 among persons aged 50 to 64 years, and a drop in coverage of 3 to 7 percentage points from the 1999–2000 to the 2000–2001 season in each subgroup (Fig. 1) ...

The highest coverage occurred during the 1999–2000 season in most subgroups: among persons with heart disease, coverage for this season was 76.7% (95% CI, 73.5%–79.9%) for persons aged 65 years and older, 49.2% (95% CI, 44.1%–54.3%) for persons aged 50 to 64 years

Influenza Vaccination Coverage Among People With High-Risk Conditions in the U.S. ... (Table 2)

Among persons with heart disease, coverage for 2012–2013 season was 50.9% (95% CI, 48.2%–53.6%) for persons aged 50 to 64 years

IMHO high risk /prior event CAD patients in the US are increasingly aggressively monitored by their healthcare providers to ensure they get the annual Flu shot and this will slow the rate of events

Based on data vs IMHO ... the influenza vaccination coverage among persons with heart disease
- for persons aged 50 to 64 years: was flat (49.2% vs 50.9%) from 1999–2000 to 2012-2013
- for persons aged 65 years and older: meanwhile no data available (?) for the recent years, due to:
> high basis: 76.7%
> flat coverage (62.7% vs 65.3%) for overall population (aged 65 years and older)
more likely, it was flat (or small increase) also ... the potential, maximum increase is ABS 23.3%, relative 30% ... to reach 100% coverage ... not likely scenario

As 32% of R-IT study locations are in non-Westen countries and (based on ANCHOR: 38.9%) the expected % of ≥65 years of age is app. 40% ... it isn't likely that the Flu shot / the "big push" of it has any effect on R-IT event rate.

Best,
G