Yes, Mycroft, it takes brass balls to invest LONG in a Baby Biotech like AVXL tackling CNS Disorders where so many others have tried and failed. I feel like I just survived Navy Seal training to say I made it through those 5 bridges you've listed. BOOYAH!! Now the stage is set for the bombs to drop, one after another and with any luck, ANAVEX 2-73 will be on its way to becoming the next Salk Vaccine for polio.... only 100 X bigger and better.