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XenaLives

09/21/17 1:49 PM

#121218 RE: OFP #121184

I think that it's been said that the MOA is not fully understood - but that is different from not known.

Please link to the source of your statement. My confidence in your assertions is non existant.


The obvious problem with this "tip of the iceberg" sentiment is that it is a recognition that the MOA is not known. Directly following from it is that the MOA narrative the company has been pushing including pretty much ALL their preclinical testing and claims of cellular homeostasis become moot.

Of course a compound tested without a logical MOA is really a shot in the dark. A priori probabilities are shot....with confidence in any finding reduced.