Multiple System Atrophy (MSA)
Is similar in some physiological effects to Parkinson's.
Therefore, Anavex 2-73 might be helpful.
The same, continuing question: Just what and how many degenerative diseases might Anavex drugs treat or prevent?
I doubt it will turn out to be only Alzheimer's, Parkinson's, and Rett.
Factual disclosure: As it happens, I have a mild case of hereditary spastic paraplegia, where my long spinal nerves controlling the adductor muscles of my legs (and a few others) remain inordinately excited, keeping me from a normal gait. Have to use a walker. No pain, just the discomfort of inhibited ambulation.
A French researcher inserted the genes for my condition in some lab rats, and sure enough, their rear legs tightened up, as with me, from the hyperexcitability of the long motor neurons controlling leg muscles used for normal gait. After a week or so of drinking water infused with Anavex 2-73, the rats lost their spasticity and walked normally. I, therefore, have every reason to believe this will work for me, too (rat, or not, that I am). Anavex sigma-1 receptor agonists have great potential for the treatment of hereditary spastic paraplegia (HSP), and a related set of conditions, primary lateral sclerosis (PLS).
I therefore have a personal non-pecuniary hope for FDA approval. (I strive to not let that influence the validity of my postings here.)
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