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Mikesc

08/24/17 3:16 PM

#117088 RE: seventhwave #117087

We don't need a phase 1 and if the drug works we will not need a phase 3. Just my humble opinion.
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Talon38

08/24/17 3:50 PM

#117093 RE: seventhwave #117087

7th, I don't believe anyone minimizes the complexity of the Rett Syndrome as well as the similar complexity for AD and PD. The success of 2-73 may be wide in scope or narrow in application but I think most on this board believe there will be success and we will move progress in curing/treating these neurodegenerative diseases forward. As to the length of drug development and human trials on the graph, it certainly does not reflect the FDA's current plans under the 21st CCA. That has been significantly accelerated to bring safe and effective drugs to bare on the terrible diseases targeted.
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XenaLives

08/24/17 5:55 PM

#117108 RE: seventhwave #117087

OK - Anavex may be able to slow progression or dampen the effects of the genetic defect which will be more than sufficient for approval.

That wouldn't mean that the Rett foundation would quit looking for a way to fix the genetic defect.

Gross over simplification - but I think you get the drift.