Replies to post #112407 on Amarin Corp Plc (AMRN)

[rafunrafun]

No, the market does not know what the placebo rate is.

[sts66]

3.5/5.9= 41%

Your calculator needs new batteries - mine says 3.5/5.9 = 59%.

I used 4.6 composite, came up with 3.3/5.9 = 56% RRR, which seems awfully high, even if you subtract from 1, which gives you 44% RRR - can't believe the trial wasn't halted at 80% IA with a PE RRR like that regardless of SEs when the trial is designed to show 15% RRR, although that's not including how p value plays into it - and the PY's is likely off too, skewing the numbers. Too lazy to figure out what numbers would be using something like 33k PY's instead of 30k, and if placebo rate was lower, like 5.6 or 5.7 - would need to create a matrix to do that.