Replies to post #113863 on Anavex Life Sciences Corp (AVXL)

[frrol]

I only got to your 1) and had to correct you right there. "1) Per chance, selected trial participants actually were all uniquely and universally super responders." I'm going to give you a chance to correct that yourself before I or someone else has to, yet again.

[nidan7500]

We read these thoughtful, well worded replies and recognize the complexity and logic of the last couple of years. We are left with strong sometimes isolated facts pointing toward a proven concept/proposition CNS Homeostasis. Is it possible that the human body can treat itself w/help from A2-73? A lot of smart people argue here yet no evidence of any agreement on facts between the two camps. They do not want to agree in some cases. It all, this will come down to answering the question on CNS Homeostasis like an old Sci-Fi movie.

Until it can be said there is solid/validated evidence that an effective treatment for CNS diseases these debates will go one. IMO, the answer is known and the FDA will be the party to break the good news, soon.

[bas2020]

Falconer, Mycroft, others,

Any comments about the following? Appears it's another attempt at inhibiting some biological process, rather than facilitating "homeostasis". Thoughts?

Pain Therapeutics’ PTI-125, Potential Treatment for Alzheimer’s, to Undergo Phase 1 Clinical Trial

According to results of a recent study, “PTI-125 reduces amyloid-related Alzheimer’s pathogenesis by targeting filamin A,” that appeared in the journal Alzheimer’s & Dementia, PTI-125 works by binding to a particular site on filamin A (FLNA), a protein critical to beta amyloid’s toxicity.

https://alzheimersnewstoday.com/2017/08/02/pain-therapeutics-ptie-reports-fda-clearance-of-investigational-new-drug-ind-application-for-pti-125/?utm_source=Alzheimer%27s+List&utm_campaign=c18e67e403-RSS_EMAIL_CAMPAIGN&utm_medium=email&utm_term=0_94425accb7-c18e67e403-71697525