Replies to post #113615 on Anavex Life Sciences Corp (AVXL)

[kld2]

good post, falconer. Frank.

[frrol]

Yes, as (or if, depending on your optimism) evidence of real therapeutic benefit piles up, interest in and coverage of the drug and company will grow accordingly. Like it always does. It just takes much longer than folks inexperienced in biotech assumed. Biotech is long term.

[F1ash]

Kudos sir! Nice post!

[OFP]

But the real reason there is such a lack of external Anavex enthusiasm is that the present levels of proofs of safety and efficacy are regarded as utterly insufficient. Not enough firm, positive data upon which to base an investment decision.

Agree and this post was far more balanced than in the past. Would you know say that your previous proclamation that 2-73 success in AD can be firmly predicted based on the available evidence was premature or do you still hold that as true?

[bas2020]

Nice summary of the situation. In addition to historical risk with Alz drug trials, institutions, by and large, also know the market games which are played in emerging biotech by MMs and hedge funds. For those reasons, many institutions have restrictions on investing in any emerging biotech/drug that is not yet in Phase 3. I predict we won't see a readout on Retts until Alz Phase 2b/3 has begun. Either event will start a strong uptrend. Though, I'm still holding out for the PK/PD readout and P2a-III updates (i.e. 18-mo) before then (looking at Anavex's list of upcoming "checkbox" milestones).

[jmvho]

Great post Falconer ! Thanks for all you do for this board.

[Bourbon_on_my_cornflakes]

Great post. Now AVXL needs to get the trials started and release more data so the current lack of confidence is removed.