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wildcard235

06/06/17 3:53 PM

#107389 RE: kld2 #107384

We do know. It's zero.

If a single patient with Alzheimer's gets better for a whole year, it is unprecedented and dramatic. If 19 of them, it is earth-shaking.

And N=19 or similar small number in an adaptive trial design is equal to a far larger number had it been a conventional trial design.
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frrol

06/06/17 9:27 PM

#107419 RE: kld2 #107384

This is why biotech stocks are so dangerous for retail investors. They just don't understand the scientific process and the fundamentals of placebo effect, Pooper and falsifiability, statistics, etc. You get posts like that and cringe.