Good pair of links, JD1. As a non-member, I think I missed that theater...
Monday, April 18, 3:00 to 4:00 P.M., AACR Exhibitor Spotlight Theater
Presenters:
Paul Tumeh, MD, Assistant Professor, UCLA Medical Center, Dept. of Medicine Clifford Hoyt, Oncology Fellow, PerkinElmer
Abstract:
Therapies that block the PD-1/PD-L1 axis have shown significant clinical activity in melanoma and other cancers. Recent evidence has shown that pre-existing CD8 T cells infiltrates at the invasive tumor margin of metastatic melanoma are associated with the presence of the PD-1/PD-L1 immune axis and may predict response to therapy. We examined the relationship between site of metastatic disease, local immune response, and treatment outcome in patients with advanced melanoma.